GC33019
AGI-24512
Also known as 6-(4-hydroxyphenyl)-5-methyl-2-phenyl-3-piperidin-1-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
AGI-24512 is a potent methionine adenosyltransferase 2α (MAT2A) inhibitor, with an IC50 of 8 nM· AGI-24512 triggers DNA damage response· AGI-24512 can block proliferation of MTAP-deleted cancer cells in vitro· AGI-24512 can be used for researching anticancer
ChemicalCAS2201066-53-5MW400.47FormulaC24H24N4O2
- CAS number
- 2201066-53-5
- Molecular weight
- 400.47
- Formula
- C24H24N4O2
- Solubility
- DMSO ： 125 mg/mL (312·13 mM);Water ： ＜ 0·1 mg/mL (insoluble)
- InChIKey
- VFEXODVWKUOZBF-UHFFFAOYSA-N
- Catalogue number
- GC33019
- Brand
- GLPBIO
Computed properties PubChem CID 134307780 · XLogP 4.1 · TPSA 68.2 Ų · H-bond donors 2
- XLogP
- 4.1
- TPSA
- 68.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 30
SMILES CC1=C(C(=O)N2C(=N1)C(=C(N2)C3=CC=CC=C3)N4CCCCC4)C5=CC=C(C=C5)O
Computed descriptors from PubChem (CID 134307780), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il