GC64539
SKLB-197
Also known as (3R)-4-[2-(1H-indol-4-yl)-6-(2-methylpyrazol-3-yl)quinazolin-4-yl]-3-methylmorpholine
SKLB-197 showed an IC50 value of 0·013 μM against ATR but very weak or no activity against other 402 protein kinases· It displayed potent antitumor activity against ATM-deficent tumors both in vitro and in vivo
ChemicalCAS2713577-16-1MW424.5FormulaC25H24N6O
- CAS number
- 2713577-16-1
- Molecular weight
- 424.5
- Formula
- C25H24N6O
- InChIKey
- FCNFJRRMUAOHKI-MRXNPFEDSA-N
- Catalogue number
- GC64539
- Brand
- GLPBIO
Computed properties PubChem CID 162641668 · XLogP 3.8 · TPSA 71.9 Ų · H-bond donors 1
- XLogP
- 3.8
- TPSA
- 71.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 32
SMILES C[C@@H]1COCCN1C2=NC(=NC3=C2C=C(C=C3)C4=CC=NN4C)C5=C6C=CNC6=CC=C5
Computed descriptors from PubChem (CID 162641668), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il