GC33141
SKLB4771 (FLT3-IN-1)
Also known as 1-(4-methylphenyl)-3-[5-[7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]sulfanyl-1,3,4-thiadiazol-2-yl]urea
SKLB4771 (FLT3-IN-1) is a potent and selective Flt3 inhibitor with an IC50 value of 10 nM· SKLB4771 (FLT3-IN-1) downregulates the phosphorylation of FLT3/STAT5/ERK, blocks cell proliferation, and induces apoptosis in tumor tissue
ChemicalCAS1370256-78-2MW537.66FormulaC25H27N7O3S2
- CAS number
- 1370256-78-2
- Molecular weight
- 537.66
- Formula
- C25H27N7O3S2
- Solubility
- DMSO ： ≥ 47 mg/mL (87·42 mM)
- InChIKey
- LKXFSTAQMOENSC-UHFFFAOYSA-N
- Catalogue number
- GC33141
- Brand
- GLPBIO
Computed properties PubChem CID 57412684 · XLogP 4 · TPSA 168 Ų · H-bond donors 2
- XLogP
- 4
- TPSA
- 168 Ų
- H-bond donors
- 2
- H-bond acceptors
- 10
- Rotatable bonds
- 9
- Heavy atoms
- 37
SMILES CC1=CC=C(C=C1)NC(=O)NC2=NN=C(S2)SC3=NC=NC4=C3C=CC(=C4)OCCCN5CCOCC5
Computed descriptors from PubChem (CID 57412684), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il