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Chemical structure of Sovleplenib

GC64279

Sovleplenib

Also known as 7-[4-(1-methylsulfonylpiperidin-4-yl)phenyl]-N-[[(2S)-morpholin-2-yl]methyl]pyrido[3,4-b]pyrazin-5-amine

Sovleplenib (HMPL-523) is a highly potent, orally available and selective SYK inhibitor with an IC50 of 25 nM· Anti-tumor activity· Sovleplenib can be used for the research of immune thrombocytopenia (ITP)

ChemicalCAS1415792-84-5MW482.6FormulaC24H30N6O3S
CAS number
1415792-84-5
Molecular weight
482.6
Formula
C24H30N6O3S
InChIKey
NJIAKNWTIVDSDA-FQEVSTJZSA-N
Catalogue number
GC64279
Brand
GLPBIO
Computed properties PubChem CID 71113742 · XLogP 1.2 · TPSA 118 Ų · H-bond donors 2
XLogP
1.2
TPSA
118 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
34

SMILES CS(=O)(=O)N1CCC(CC1)C2=CC=C(C=C2)C3=CC4=NC=CN=C4C(=N3)NC[C@@H]5CNCCO5

Computed descriptors from PubChem (CID 71113742), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.