Loading...
Chemical structure of Sotuletinib hydrochloride

GC69931

Sotuletinib hydrochloride

Also known as 4-[[2-[[(1R,2R)-2-hydroxycyclohexyl]amino]-1,3-benzothiazol-6-yl]oxy]-N-methylpyridine-2-carboxamide;hydrochloride

Sotuletinib (BLZ945) is an effective, selective, and brain-penetrant inhibitor of CSF-1R (c-Fms), with an IC50 of 1 nM and a selectivity that is 1000 times greater than other receptor tyrosine kinases

ChemicalCAS2222138-31-8MW434.94FormulaC20H23ClN4O3S
CAS number
2222138-31-8
Molecular weight
434.94
Formula
C20H23ClN4O3S
Solubility
H2O ： 100 mg/mL (229·92 mM; Need ultrasonic)
InChIKey
IHWOVMRZEIHNGY-SATBOSKTSA-N
Catalogue number
GC69931
Brand
GLPBIO
Computed properties PubChem CID 141759984 · TPSA 125 Ų · H-bond donors 4 · H-bond acceptors 7
TPSA
125 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
29

SMILES CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)N[C@@H]4CCCC[C@H]4O.Cl

Computed descriptors from PubChem (CID 141759984), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.