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Chemical structure of Sovesudil

GC63351

Sovesudil

Also known as propyl 3-[2-(aminomethyl)-5-[(3-fluoro-4-pyridinyl)carbamoyl]phenyl]benzoate

Sovesudil (PHP-201) is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor with IC50s of 3·7 and 2·3 nM for ROCK-I and ROCK-II, respectively

ChemicalCAS1333400-14-8MW407.44FormulaC23H22FN3O3
CAS number
1333400-14-8
Molecular weight
407.44
Formula
C23H22FN3O3
Solubility
DMSO ： 100 mg/mL (245·43 mM; Need ultrasonic)
InChIKey
PNWBYIFLWUCWKS-UHFFFAOYSA-N
Catalogue number
GC63351
Brand
GLPBIO
Computed properties PubChem CID 68245749 · XLogP 3 · TPSA 94.3 Ų · H-bond donors 2
XLogP
3
TPSA
94.3 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
30

SMILES CCCOC(=O)C1=CC=CC(=C1)C2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3)F)CN

Computed descriptors from PubChem (CID 68245749), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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