Loading...
Chemical structure of GSK3494245

GC64213

GSK3494245

Also known as N-[4-fluoro-3-(3-morpholin-4-ylimidazo[1,2-a]pyrimidin-7-yl)phenyl]pyrrolidine-1-carboxamide

GSK3494245 (DDD01305143) is a potent, orally active, and selective inhibitor of the chymotrypsin-like activity of the parasite proteasome binding in a site sandwiched between the β4 and β5 subunits (IC50=0·16 μM for WT L

ChemicalCAS2080410-41-7MW410.44FormulaC21H23FN6O2
CAS number
2080410-41-7
Molecular weight
410.44
Formula
C21H23FN6O2
Solubility
DMSO ： 100 mg/mL (243·64 mM; Need ultrasonic)
InChIKey
SAJUCKZZYFFICP-UHFFFAOYSA-N
Catalogue number
GC64213
Brand
GLPBIO
Computed properties PubChem CID 126571915 · XLogP 2.6 · TPSA 75 Ų · H-bond donors 1
XLogP
2.6
TPSA
75 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
30

SMILES C1CCN(C1)C(=O)NC2=CC(=C(C=C2)F)C3=NC4=NC=C(N4C=C3)N5CCOCC5

Computed descriptors from PubChem (CID 126571915), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.