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Chemical structure of TMX-4100

GC63520

TMX-4100

Also known as 3-(4-thiophen-3-yltriazol-1-yl)piperidine-2,6-dione

TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader· TMX-4100 shows a high degradation preference for PDE6D with the DC50 values less than 200 nM in MOLT4, Jurkat, and MM·1S cells· TMX-4100 can be used for the research of multiple myeloma

ChemicalCAS2367619-63-2MW262.29FormulaC11H10N4O2S
CAS number
2367619-63-2
Molecular weight
262.29
Formula
C11H10N4O2S
InChIKey
PGEUBQZQGXWTFO-UHFFFAOYSA-N
Catalogue number
GC63520
Brand
GLPBIO
Computed properties PubChem CID 151449452 · XLogP 0.4 · TPSA 105 Ų · H-bond donors 1
XLogP
0.4
TPSA
105 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
18

SMILES C1CC(=O)NC(=O)C1N2C=C(N=N2)C3=CSC=C3

Computed descriptors from PubChem (CID 151449452), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.