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Chemical structure of CDK12-IN-2

GC63499

CDK12-IN-2

Also known as 3-benzyl-1-[4-[(5-cyano-2-pyridinyl)amino]cyclohexyl]-1-[4-(1-methyl-6-oxo-3-pyridinyl)phenyl]urea

CDK12-IN-2 is a potent, selective and nanomolar CDK12 inhibitor (IC50=52 nM) with good physicochemical properties

ChemicalCAS2244987-03-7MW532.64FormulaC32H32N6O2
CAS number
2244987-03-7
Molecular weight
532.64
Formula
C32H32N6O2
InChIKey
HDJBGURZVALLMD-UHFFFAOYSA-N
Catalogue number
GC63499
Brand
GLPBIO
Computed properties PubChem CID 134813906 · XLogP 4.2 · TPSA 101 Ų · H-bond donors 2
XLogP
4.2
TPSA
101 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
40

SMILES CN1C=C(C=CC1=O)C2=CC=C(C=C2)N(C3CCC(CC3)NC4=NC=C(C=C4)C#N)C(=O)NCC5=CC=CC=C5

Computed descriptors from PubChem (CID 134813906), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.