GC60103
CDK12-IN-E9
Also known as N-[3-[[3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]phenyl]prop-2-enamide
CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and a non-covalent CDK9 inhibitor, while avoiding ABC transporter-mediated efflux· CDK12-IN-E9 has weak binding ability to CDK7/CyclinH complex with an IC50> 1 μM
ChemicalCAS2020052-55-3MW434.53FormulaC24H30N6O2
- CAS number
- 2020052-55-3
- Molecular weight
- 434.53
- Formula
- C24H30N6O2
- InChIKey
- CDCHESFKYUNJPV-FQEVSTJZSA-N
- Catalogue number
- GC60103
- Brand
- GLPBIO
Computed properties PubChem CID 122596923 · XLogP 3.8 · TPSA 94.8 Ų · H-bond donors 3
- XLogP
- 3.8
- TPSA
- 94.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Rotatable bonds
- 8
- Heavy atoms
- 32
SMILES CCC1=C2N=C(C=C(N2N=C1)NC3=CC(=CC=C3)NC(=O)C=C)N4CCCC[C@H]4CCO
Computed descriptors from PubChem (CID 122596923), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il