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Chemical structure of IV-361

GC63460

IV-361

Also known as N-(5-fluoro-2-methylphenyl)-6,6-dimethyl-3-[(1-trimethylsilylcyclobutanecarbonyl)amino]-1,4-dihydropyrrolo[3,4-d]pyrazole-5-carboxamide

IV-361 is an orally active and selective CDK7 inhibitor (Ki≤50 nM)· IV-361 has anti-cancer activity (US20190256531A1)

ChemicalCAS2055741-39-2MW457.62FormulaC23H32FN5O2Si
CAS number
2055741-39-2
Molecular weight
457.62
Formula
C23H32FN5O2Si
Solubility
DMSO ： 90 mg/mL (196·67 mM; Need ultrasonic)
InChIKey
FYIUNJAFLWNBAI-UHFFFAOYSA-N
Catalogue number
GC63460
Brand
GLPBIO
Computed properties PubChem CID 140882977 · TPSA 90.1 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
90.1 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
32

SMILES CC1=C(C=C(C=C1)F)NC(=O)N2CC3=C(C2(C)C)NN=C3NC(=O)C4(CCC4)[Si](C)(C)C

Computed descriptors from PubChem (CID 140882977), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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