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Chemical structure of IWP-2

GC16454

IWP-2

Also known as N-(6-methyl-1,3-benzothiazol-2-yl)-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide

IWP-2 is a specific inhibitor of Porcupine enzyme in the Wnt signaling pathway, with an IC50 value of 27 nM

ChemicalCAS686770-61-6MW466.6FormulaC22H18N4O2S3
CAS number
686770-61-6
Molecular weight
466.6
Formula
C22H18N4O2S3
Solubility
≥ 23·35 mg/mL in DMF with gentle warming
InChIKey
WRKPZSMRWPJJDH-UHFFFAOYSA-N
Catalogue number
GC16454
Brand
GLPBIO
Computed properties PubChem CID 2155128 · XLogP 4.8 · TPSA 154 Ų · H-bond donors 1
XLogP
4.8
TPSA
154 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
31

SMILES CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4

Computed descriptors from PubChem (CID 2155128), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.