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Chemical structure of Mal-PEG4-Val-Cit-PAB

GC69430

Mal-PEG4-Val-Cit-PAB

Also known as (2S)-5-(carbamoylamino)-2-[[(2S)-2-[3-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-methylbutanoyl]amino]-N-[4-(hydroxymethyl)phenyl]pentanamide

Mal-PEG4-Val-Cit-PAB is a degradable ADC linker containing a maleimide group, which can be used to synthesize antibody conjugated active molecules (ADCs)

ChemicalCAS1949793-41-2MW777.86FormulaC36H55N7O12
CAS number
1949793-41-2
Molecular weight
777.86
Formula
C36H55N7O12
Solubility
DMSO : 83·33 mg/mL (107·13 mM; ultrasonic and warming and heat to 60°C)
InChIKey
PEGLOOGTSQEDBL-UVMMSNCQSA-N
Catalogue number
GC69430
Brand
GLPBIO
Computed properties PubChem CID 129280705 · XLogP -2.4 · TPSA 266 Ų · H-bond donors 7
XLogP
-2.4
TPSA
266 Ų
H-bond donors
7
H-bond acceptors
12
Rotatable bonds
29
Heavy atoms
55

SMILES CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)NC(=O)CCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O

Computed descriptors from PubChem (CID 129280705), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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