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Chemical structure of M435-1279

GC63363

M435-1279

Also known as 4-hydroxy-2-oxo-N-(4-sulfamoylphenyl)-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-b]pyridine-3-carboxamide

M435-1279 is a UBE2T inhibitor· M435-1279 inhibits the Wnt/β-catenin signaling pathway hyperactivation through blocking UBE2T-mediated degradation of RACK1

ChemicalCAS1359431-16-5MW419.47FormulaC18H17N3O5S2
CAS number
1359431-16-5
Molecular weight
419.47
Formula
C18H17N3O5S2
InChIKey
MVQJFYRZMPKNIV-UHFFFAOYSA-N
Catalogue number
GC63363
Brand
GLPBIO
Computed properties PubChem CID 54733438 · XLogP 2.1 · TPSA 175 Ų · H-bond donors 4
XLogP
2.1
TPSA
175 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
28

SMILES C1CCC2=C(C1)C3=C(S2)NC(=O)C(=C3O)C(=O)NC4=CC=C(C=C4)S(=O)(=O)N

Computed descriptors from PubChem (CID 54733438), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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