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Chemical structure of M4205

GC62314

M4205

Also known as N-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine

M4205 is a c-KIT inhibitor, with an IC50 of 10 nM for c-KIT V654A· M4205 has high activity on c-KIT mutations in exon 11, 13, 17

ChemicalCAS2590556-80-0MW508.62FormulaC29H32N8O
CAS number
2590556-80-0
Molecular weight
508.62
Formula
C29H32N8O
Solubility
DMSO ： 11·11 mg/mL (21·84 mM; ultrasonic and warming and heat to 66°C)
InChIKey
LVMAULGVWBINFP-UHFFFAOYSA-N
Catalogue number
GC62314
Brand
GLPBIO
Computed properties PubChem CID 155587867 · XLogP 4.3 · TPSA 85.4 Ų · H-bond donors 1
XLogP
4.3
TPSA
85.4 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
38

SMILES CN1C=C(C=N1)C2=CC=C(C=C2)CNC3=NC=NC(=C3)C4=CN=C5N4C=CC(=C5)OCCCN6CCCC6

Computed descriptors from PubChem (CID 155587867), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.