GC63210
TAS-117
Also known as 3-amino-1-methyl-3-[4-(5-phenyl-8-oxa-3,6,12-triazatricyclo[7.4.0.02,6]trideca-1(9),2,4,10,12-pentaen-4-yl)phenyl]cyclobutan-1-ol
TAS-117 is a potent, selective, orally active allosteric Akt inhibitor (with IC50s of 4·8, 1·6, and 44 nM for Akt1, 2, and 3, respectively)· TAS-117 triggers anti-myeloma activities and enhances fatal endoplasmic reticulum (ER) stress induced by proteasome inhibition· TAS-117 induces apoptosis and autophagy
ChemicalCAS1402602-94-1MW424.49FormulaC26H24N4O2
- CAS number
- 1402602-94-1
- Molecular weight
- 424.49
- Formula
- C26H24N4O2
- InChIKey
- AIFGVDXMHWGOGJ-UHFFFAOYSA-N
- Catalogue number
- GC63210
- Brand
- GLPBIO
Computed properties PubChem CID 66555816 · XLogP 2.5 · TPSA 86.2 Ų · H-bond donors 2
- XLogP
- 2.5
- TPSA
- 86.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 32
SMILES CC1(CC(C1)(C2=CC=C(C=C2)C3=C(N4COC5=C(C4=N3)C=NC=C5)C6=CC=CC=C6)N)O
Computed descriptors from PubChem (CID 66555816), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il