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Chemical structure of TAS-115 mesylate

GC33273

TAS-115 mesylate

Also listed as TAS-115 mesylate (TAS-115 methanesulfonate)

Pamufetinib (TAS-115) mesylate is a potent VEGFRand hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase inhibitor, with IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively

ChemicalCAS1688673-09-7MW614.66FormulaC28H27FN4O7S2
CAS number
1688673-09-7
Molecular weight
614.66
Formula
C28H27FN4O7S2
Solubility
DMSO : 75 mg/mL (122·02 mM)
InChIKey
NUYQWFCUOAVQAL-UHFFFAOYSA-N
Catalogue number
GC33273
Brand
GLPBIO
Computed properties PubChem CID 118130255 · TPSA 196 Ų · H-bond donors 4 · H-bond acceptors 10
TPSA
196 Ų
H-bond donors
4
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
42

SMILES CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=C(C=C(C=C3)NC(=S)NC(=O)CC4=CC=CC=C4)F.CS(=O)(=O)O

Computed descriptors from PubChem (CID 118130255), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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