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Chemical structure of LY3154207

GC63052

LY3154207

Also known as 2-(2,6-dichlorophenyl)-1-[(1S,3R)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl]ethanone

LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptorpositive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM)

ChemicalCAS1638667-79-4MW450.4FormulaC24H29Cl2NO3
CAS number
1638667-79-4
Molecular weight
450.4
Formula
C24H29Cl2NO3
Solubility
DMSO ： 110 mg/mL (244·23 mM; Need ultrasonic)
InChIKey
XHCSBQBBGNQINS-DOTOQJQBSA-N
Catalogue number
GC63052
Brand
GLPBIO
Computed properties PubChem CID 86290953 · XLogP 4.4 · TPSA 60.8 Ų · H-bond donors 2
XLogP
4.4
TPSA
60.8 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
30

SMILES C[C@H]1C2=CC=CC(=C2C[C@@H](N1C(=O)CC3=C(C=CC=C3Cl)Cl)CO)CCC(C)(C)O

Computed descriptors from PubChem (CID 86290953), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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