GC19235
LY3214996
Also known as 6,6-dimethyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5-(2-morpholin-4-ylethyl)thieno[2,3-c]pyrrol-4-one
LY3214996 (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays· LY3214996 potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines· LY3214996 shows potent antitumor activities in cancer models with MAPK pathway alterations
ChemicalCAS1951483-29-6MW453.56FormulaC22H27N7O2S
- CAS number
- 1951483-29-6
- Molecular weight
- 453.56
- Formula
- C22H27N7O2S
- Solubility
- DMSO ： 20 mg/mL (44·10 mM)
- InChIKey
- JNPRPMBJODOFEC-UHFFFAOYSA-N
- Catalogue number
- GC19235
- Brand
- GLPBIO
Computed properties PubChem CID 121408882 · XLogP 1.4 · TPSA 117 Ų · H-bond donors 1
- XLogP
- 1.4
- TPSA
- 117 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Rotatable bonds
- 6
- Heavy atoms
- 32
SMILES CC1(C2=C(C=C(S2)C3=NC(=NC=C3)NC4=CC=NN4C)C(=O)N1CCN5CCOCC5)C
Computed descriptors from PubChem (CID 121408882), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il