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Chemical structure of LY3177833

GC19233

LY3177833

Also known as (3R)-3-(5-fluoropyrimidin-4-yl)-3-methyl-6-(1H-pyrazol-4-yl)-2H-isoindol-1-one

LY3177833 is an CDC7 and pMCM2 inhibitor extracted from patent US 20140275131and patent WO 2014143601 A1 compound example 4; has IC50 values of 3·3 nM and 290 nM, respectively

ChemicalCAS1627696-51-8MW309.3FormulaC16H12FN5O
CAS number
1627696-51-8
Molecular weight
309.3
Formula
C16H12FN5O
Solubility
DMSO : ≥ 30 mg/mL (96·99 mM)
InChIKey
KNLVLWZENYQYRT-MRXNPFEDSA-N
Catalogue number
GC19233
Brand
GLPBIO
Computed properties PubChem CID 81689696 · XLogP 1 · TPSA 83.6 Ų · H-bond donors 2
XLogP
1
TPSA
83.6 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
23

SMILES C[C@@]1(C2=C(C=C(C=C2)C3=CNN=C3)C(=O)N1)C4=NC=NC=C4F

Computed descriptors from PubChem (CID 81689696), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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