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Chemical structure of GSK-872 hydrochloride

GC62997

GSK-872 hydrochloride

Also known as N-(6-propan-2-ylsulfonylquinolin-4-yl)-1,3-benzothiazol-5-amine;hydrochloride

GSK-872 hydrochloride is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1·8 nM, and inhibits kinase activity with an IC50 of 1·3 nM

ChemicalCAS2703752-81-0MW419.95FormulaC19H18ClN3O2S2
CAS number
2703752-81-0
Molecular weight
419.95
Formula
C19H18ClN3O2S2
Solubility
DMSO ： 10 mg/mL (23·81 mM; ultrasonic and warming and heat to 60°C)|Water ： 2·5 mg/mL (5·95 mM; ultrasonic and warming and heat to 60°C)
InChIKey
VKCVPZFWFZKUJY-UHFFFAOYSA-N
Catalogue number
GC62997
Brand
GLPBIO
Computed properties PubChem CID 155971189 · TPSA 109 Ų · H-bond donors 2 · H-bond acceptors 6
TPSA
109 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
27

SMILES CC(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=CC4=C(C=C3)SC=N4.Cl

Computed descriptors from PubChem (CID 155971189), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.