GC62635
GGTI-2154 hydrochloride
Also known as (2S)-2-[[4-(1H-imidazol-5-ylmethylamino)-2-(2-methylphenyl)benzoyl]amino]-4-methylpentanoic acid;hydrochloride
GGTI-2154 hydrochloride is a potent and selective inhibitor geranylgeranyltransferase I (GGTase I), with an IC50 of 21 nM· GGTI-2154 hydrochloride shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM)· GGTI-2154 hydrochloride can be used for the research of cancer
ChemicalCAS478908-50-8MW456.97FormulaC24H29ClN4O3
- CAS number
- 478908-50-8
- Molecular weight
- 456.97
- Formula
- C24H29ClN4O3
- Solubility
- DMSO ： 250 mg/mL (547·08 mM; Need ultrasonic)
- InChIKey
- JQRKKNPKMYXQRS-FTBISJDPSA-N
- Catalogue number
- GC62635
- Brand
- GLPBIO
Computed properties PubChem CID 69892739 · TPSA 107 Ų · H-bond donors 5 · H-bond acceptors 5
- TPSA
- 107 Ų
- H-bond donors
- 5
- H-bond acceptors
- 5
- Rotatable bonds
- 9
- Heavy atoms
- 32
SMILES CC1=CC=CC=C1C2=C(C=CC(=C2)NCC3=CN=CN3)C(=O)N[C@@H](CC(C)C)C(=O)O.Cl
Computed descriptors from PubChem (CID 69892739), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il