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Chemical structure of GGTI-2154

GC62633

GGTI-2154

Also known as (2S)-2-[[4-(1H-imidazol-5-ylmethylamino)-2-(2-methylphenyl)benzoyl]amino]-4-methylpentanoic acid

GGTI-2154 is a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I), with an IC50 of 21 nM· GGTI-2154 shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM)· GGTI-2154 can be used for the research of cancer

ChemicalCAS251577-10-3MW420.5FormulaC24H28N4O3
CAS number
251577-10-3
Molecular weight
420.5
Formula
C24H28N4O3
InChIKey
GAJLKAVQYXFCRU-QFIPXVFZSA-N
Catalogue number
GC62633
Brand
GLPBIO
Computed properties PubChem CID 10387426 · XLogP 4.2 · TPSA 107 Ų · H-bond donors 4
XLogP
4.2
TPSA
107 Ų
H-bond donors
4
H-bond acceptors
5
Rotatable bonds
9
Heavy atoms
31

SMILES CC1=CC=CC=C1C2=C(C=CC(=C2)NCC3=CN=CN3)C(=O)N[C@@H](CC(C)C)C(=O)O

Computed descriptors from PubChem (CID 10387426), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.