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Chemical structure of ASK120067

GC62402

ASK120067

Also known as N-[5-[[5-chloro-4-(naphthalen-2-ylamino)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]-4-methoxyphenyl]prop-2-enamide

ASK120067 (ASK120067) is a potent and orally active inhibitor of EGFRT790M (IC50:0·3 nM) with selectivity over EGFRWT (IC50:6·0 nM)· ASK120067 is a third-generation EGFR-TKI for the research ofnon-small cell lung cancer (NSCLC)

ChemicalCAS1934259-00-3MW546.06FormulaC29H32ClN7O2
CAS number
1934259-00-3
Molecular weight
546.06
Formula
C29H32ClN7O2
Solubility
DMSO : 100 mg/mL (183·13 mM; Need ultrasonic)
InChIKey
QHPVTCLSVVUPOF-UHFFFAOYSA-N
Catalogue number
GC62402
Brand
GLPBIO
Computed properties PubChem CID 121371196 · XLogP 5.7 · TPSA 94.7 Ų · H-bond donors 3
XLogP
5.7
TPSA
94.7 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
11
Heavy atoms
39

SMILES CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=C(C(=N2)NC3=CC4=CC=CC=C4C=C3)Cl)OC

Computed descriptors from PubChem (CID 121371196), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.