Loading...
Chemical structure of ASK1-IN-2

GC62426

ASK1-IN-2

Also known as 6-fluoro-N-[6-(4-propan-2-yl-1,2,4-triazol-3-yl)-2-pyridinyl]-1H-indole-2-carboxamide

ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32·8 nM

ChemicalCAS2541792-70-3MW364.38FormulaC19H17FN6O
CAS number
2541792-70-3
Molecular weight
364.38
Formula
C19H17FN6O
Solubility
DMSO ： 250 mg/mL (686·10 mM; Need ultrasonic)
InChIKey
LYUQNMNUBOUCBX-UHFFFAOYSA-N
Catalogue number
GC62426
Brand
GLPBIO
Computed properties PubChem CID 155671000 · XLogP 2.5 · TPSA 88.5 Ų · H-bond donors 2
XLogP
2.5
TPSA
88.5 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
27

SMILES CC(C)N1C=NN=C1C2=NC(=CC=C2)NC(=O)C3=CC4=C(N3)C=C(C=C4)F

Computed descriptors from PubChem (CID 155671000), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.