GC38463
ASLAN003
Also known as 2-[2,6-difluoro-4-(3-methoxyphenyl)anilino]pyridine-3-carboxylic acid
ASLAN003 (ASLAN003) is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for human DHODH enzyme· ASLAN003 inhibits protein synthesis via activation of AP-1 transcription factors· ASLAN003 induces apoptosis and substantially prolongs survival in acute myeloid leukemia (AML) xenograft mice
ChemicalCAS1035688-66-4MW356.32FormulaC19H14F2N2O3
- CAS number
- 1035688-66-4
- Molecular weight
- 356.32
- Formula
- C19H14F2N2O3
- Solubility
- DMSO： 130 mg/mL (364·84 mM)
- InChIKey
- OMPATGZMNFWVOH-UHFFFAOYSA-N
- Catalogue number
- GC38463
- Brand
- GLPBIO
Computed properties PubChem CID 24986824 · XLogP 4.6 · TPSA 71.5 Ų · H-bond donors 2
- XLogP
- 4.6
- TPSA
- 71.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 5
- Heavy atoms
- 26
SMILES COC1=CC=CC(=C1)C2=CC(=C(C(=C2)F)NC3=C(C=CC=N3)C(=O)O)F
Computed descriptors from PubChem (CID 24986824), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il