Loading...
Chemical structure of AS1708727

GC62309

AS1708727

Also known as 2-cyclopentyl-N-[2,4-dichloro-3-(isoquinolin-5-yloxymethyl)phenyl]-N-methylacetamide

AS1708727 is an orally active Foxo1 inhibitor, with EC50 values of 0·33 μM and 0·59 μM for G6Pase and PEPCK, respectively

ChemicalCAS1253226-93-5MW443.37FormulaC24H24Cl2N2O2
CAS number
1253226-93-5
Molecular weight
443.37
Formula
C24H24Cl2N2O2
Solubility
DMSO ： 41·67 mg/mL (93·98 mM; Need ultrasonic)
InChIKey
OZEZQEPCCWFFJQ-UHFFFAOYSA-N
Catalogue number
GC62309
Brand
GLPBIO
Computed properties PubChem CID 49787159 · XLogP 6.3 · TPSA 42.4 Ų · H-bond donors 0
XLogP
6.3
TPSA
42.4 Ų
H-bond donors
0
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
30

SMILES CN(C1=C(C(=C(C=C1)Cl)COC2=CC=CC3=C2C=CN=C3)Cl)C(=O)CC4CCCC4

Computed descriptors from PubChem (CID 49787159), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.