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Chemical structure of AS1517499

GC19039

AS1517499

Also known as 4-(benzylamino)-2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidine-5-carboxamide

AS1517499 is a potent and brain-permeable STAT6 inhibitor with IC50 of 21 nM· AS1517499 often plays a role in the treatment of renal fibrosis and Keloids

ChemicalCAS919486-40-1MW397.86FormulaC20H20ClN5O2
CAS number
919486-40-1
Molecular weight
397.86
Formula
C20H20ClN5O2
Solubility
DMSO ： ≥ 35 mg/mL (87·97 mM)
InChIKey
OZRMEKAUZBKTTC-UHFFFAOYSA-N
Catalogue number
GC19039
Brand
GLPBIO
Computed properties PubChem CID 10340781 · XLogP 4 · TPSA 113 Ų · H-bond donors 4
XLogP
4
TPSA
113 Ų
H-bond donors
4
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
28

SMILES C1=CC=C(C=C1)CNC2=NC(=NC=C2C(=O)N)NCCC3=CC(=C(C=C3)O)Cl

Computed descriptors from PubChem (CID 10340781), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.