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Chemical structure of AS2863619

GC38736

AS2863619

Also known as 4-[1-(2-methyl-3H-benzimidazol-5-yl)imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine;dihydrochloride

AS2863619 is an orally administered small molecule inhibitor of cyclin-dependent kinase (CDK) 8 and 19 with IC50 of 0·6099nM and 4·277nM, respectively

ChemicalCAS2241300-51-4MW405.24FormulaC16H14Cl2N8O
CAS number
2241300-51-4
Molecular weight
405.24
Formula
C16H14Cl2N8O
Solubility
DMSO： 250 mg/mL (616·92 mM)
InChIKey
LHUAALWRORLTCJ-UHFFFAOYSA-N
Catalogue number
GC38736
Brand
GLPBIO
Computed properties PubChem CID 139600293 · TPSA 124 Ų · H-bond donors 4 · H-bond acceptors 7
TPSA
124 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
2
Heavy atoms
27

SMILES CC1=NC2=C(N1)C=C(C=C2)N3C4=C(C=NC=C4)N=C3C5=NON=C5N.Cl.Cl

Computed descriptors from PubChem (CID 139600293), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.