
GC61454
GW806742X hydrochloride
GW806742X hydrochloride, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9·3 μM· GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM)· GW806742X hydrochloride retards MLKL membrane translocation and inhibits necroptosis
ChemicalMW610.01FormulaC25H23ClF3N7O4S
- CAS number
- —
- Molecular weight
- 610.01
- Formula
- C25H23ClF3N7O4S
- Solubility
- DMSO: 100 mg/mL (163·93 mM); Water: < 0·1 mg/mL (ultrasonic) (insoluble)
- Catalogue number
- GC61454
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il