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Chemical structure of GW806742X hydrochloride

GC61454

GW806742X hydrochloride

GW806742X hydrochloride, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9·3 μM· GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM)· GW806742X hydrochloride retards MLKL membrane translocation and inhibits necroptosis

ChemicalMW610.01FormulaC25H23ClF3N7O4S
CAS number
Molecular weight
610.01
Formula
C25H23ClF3N7O4S
Solubility
DMSO: 100 mg/mL (163·93 mM); Water: < 0·1 mg/mL (ultrasonic) (insoluble)
Catalogue number
GC61454
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.