Loading...
Chemical structure of GW806742X

GC36203

GW806742X

Also known as 1-[4-[methyl-[2-(3-sulfamoylanilino)pyrimidin-4-yl]amino]phenyl]-3-[4-(trifluoromethoxy)phenyl]urea

GW806742X, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9·3 μM

ChemicalCAS579515-63-2MW573.55FormulaC25H22F3N7O4S
CAS number
579515-63-2
Molecular weight
573.55
Formula
C25H22F3N7O4S
Solubility
DMSO： ≥ 125 mg/mL (217·94 mM)
InChIKey
SNRUTMWCDZHKKM-UHFFFAOYSA-N
Catalogue number
GC36203
Brand
GLPBIO
Computed properties PubChem CID 5329829 · XLogP 4.4 · TPSA 160 Ų · H-bond donors 4
XLogP
4.4
TPSA
160 Ų
H-bond donors
4
H-bond acceptors
12
Rotatable bonds
8
Heavy atoms
40

SMILES CN(C1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)OC(F)(F)F)C3=NC(=NC=C3)NC4=CC(=CC=C4)S(=O)(=O)N

Computed descriptors from PubChem (CID 5329829), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.