Loading...
Chemical structure of ICCB280

GC61414

ICCB280

Also known as 2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3-(2-methoxyphenyl)quinazolin-4-one

ICCB280 is a potent inducer of C/EBPα· ICCB280 exhibits anti-leukemic properties including terminal differentiation, proliferation arrest, and apoptosis through activation of C/EBPα and affecting its downstream targets (such as C/EBPε, G-CSFR and c-Myc)

ChemicalCAS2041072-41-5MW386.4FormulaC23H18N2O4
CAS number
2041072-41-5
Molecular weight
386.4
Formula
C23H18N2O4
Solubility
DMSO： 83·33 mg/mL (215·66 mM)
InChIKey
OTKDKQJFWIGZLU-ACCUITESSA-N
Catalogue number
GC61414
Brand
GLPBIO
Computed properties PubChem CID 135500267 · XLogP 3.8 · TPSA 82.4 Ų · H-bond donors 2
XLogP
3.8
TPSA
82.4 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
29

SMILES COC1=CC=CC=C1N2C(=NC3=CC=CC=C3C2=O)/C=C/C4=CC(=C(C=C4)O)O

Computed descriptors from PubChem (CID 135500267), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.