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Chemical structure of ICA-27243

GC39293

ICA-27243

Also known as N-(6-chloro-3-pyridinyl)-3,4-difluorobenzamide

ICA-27243 is a selective, potent and orally active KCNQ2/Q3 potassium channel opener with an EC50 of 0·38 μM

ChemicalCAS325457-89-4MW268.65FormulaC12H7ClF2N2O
CAS number
325457-89-4
Molecular weight
268.65
Formula
C12H7ClF2N2O
Solubility
DMSO: 250 mg/mL (930·58 mM)
InChIKey
GDGUOCFTHNGPBK-UHFFFAOYSA-N
Catalogue number
GC39293
Brand
GLPBIO
Computed properties PubChem CID 9903497 · XLogP 2.8 · TPSA 42 Ų · H-bond donors 1
XLogP
2.8
TPSA
42 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
18

SMILES C1=CC(=C(C=C1C(=O)NC2=CN=C(C=C2)Cl)F)F

Computed descriptors from PubChem (CID 9903497), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.