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Chemical structure of VTP50469

GC61376

VTP50469

Also known as 5-fluoro-2-[4-[7-[[4-(methanesulfonamido)cyclohexyl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl]oxy-N,N-di(propan-2-yl)benzamide

VTP50469 is a small-molecule inhibitor of the Menin-MLL protein-protein interaction with a Ki of 104 pM

ChemicalCAS2169916-18-9MW630.82FormulaC32H47FN6O4S
CAS number
2169916-18-9
Molecular weight
630.82
Formula
C32H47FN6O4S
Solubility
DMSO： 125 mg/mL (198·15 mM)
InChIKey
ADHHOUXZPBYYSU-UHFFFAOYSA-N
Catalogue number
GC61376
Brand
GLPBIO
Computed properties PubChem CID 132212900 · XLogP 4.4 · TPSA 116 Ų · H-bond donors 1
XLogP
4.4
TPSA
116 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
10
Heavy atoms
44

SMILES CC(C)N(C(C)C)C(=O)C1=C(C=CC(=C1)F)OC2=CN=CN=C2N3CC4(C3)CCN(CC4)CC5CCC(CC5)NS(=O)(=O)C

Computed descriptors from PubChem (CID 132212900), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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