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Chemical structure of VT-105

GC75792

VT-105

Also known as N-[(1S)-1-pyridin-2-ylethyl]-8-[4-(trifluoromethyl)phenyl]quinoline-3-carboxamide

VT-105 is a potent and selective TEAD autopalmitoylation inhibitor that inhibits proliferation and tumor growth in NF2-deficient mesothelioma

ChemicalCAS2417718-38-6MW421.41FormulaC24H18F3N3O
CAS number
2417718-38-6
Molecular weight
421.41
Formula
C24H18F3N3O
Solubility
DMSO: ≥ 100 mg/mL (237·30 mM)
InChIKey
FUKXXBXVSANFJK-HNNXBMFYSA-N
Catalogue number
GC75792
Brand
GLPBIO
Computed properties PubChem CID 153583357 · XLogP 4.8 · TPSA 54.9 Ų · H-bond donors 1
XLogP
4.8
TPSA
54.9 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
31

SMILES C[C@@H](C1=CC=CC=N1)NC(=O)C2=CN=C3C(=C2)C=CC=C3C4=CC=C(C=C4)C(F)(F)F

Computed descriptors from PubChem (CID 153583357), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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