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Chemical structure of PROTAC RIPK degrader-6

GC61215

PROTAC RIPK degrader-6

Also known as 2-[2-[2-[2-[2-[4-(1,3-benzothiazol-5-ylamino)-6-tert-butylsulfonylquinolin-7-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]acetamide

PROTAC RIPK degrader-6 (example 1) is a Cereblon-based PROTAC targeting RIP Kinase degradation wherein the RIP2 kinase inhibitor is linked via a linker to a cereblon binder

ChemicalCAS2089205-64-9MW889FormulaC43H48N6O11S2
CAS number
2089205-64-9
Molecular weight
889
Formula
C43H48N6O11S2
Solubility
DMSO： 100 mg/mL (112·49 mM)
InChIKey
BRZGXSNAXRPPFI-UHFFFAOYSA-N
Catalogue number
GC61215
Brand
GLPBIO
Computed properties PubChem CID 126696039 · XLogP 3 · TPSA 250 Ų · H-bond donors 3
XLogP
3
TPSA
250 Ų
H-bond donors
3
H-bond acceptors
15
Rotatable bonds
21
Heavy atoms
62

SMILES CC(C)(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1OCCOCCOCCOCCOCC(=O)NC3=CC=CC4=C3CN(C4=O)C5CCC(=O)NC5=O)NC6=CC7=C(C=C6)SC=N7

Computed descriptors from PubChem (CID 126696039), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.