Loading...
Chemical structure of FTI-2153

GC60861

FTI-2153

Also known as methyl (2S)-2-[[4-[(1H-imidazol-5-ylmethylamino)methyl]-2-(2-methylphenyl)benzoyl]amino]-4-methylsulfanylbutanoate

FTI-2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1·4 nM· FTI-2153 is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing· Anti-cancer activity

ChemicalCAS344900-92-1MW466.6FormulaC25H30N4O3S
CAS number
344900-92-1
Molecular weight
466.6
Formula
C25H30N4O3S
Solubility
DMSO： 100 mg/mL (214·32 mM)
InChIKey
KZCMMZOLCBZLNG-QHCPKHFHSA-N
Catalogue number
GC60861
Brand
GLPBIO
Computed properties PubChem CID 6918458 · XLogP 3.2 · TPSA 121 Ų · H-bond donors 3
XLogP
3.2
TPSA
121 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
12
Heavy atoms
33

SMILES CC1=CC=CC=C1C2=C(C=CC(=C2)CNCC3=CN=CN3)C(=O)N[C@@H](CCSC)C(=O)OC

Computed descriptors from PubChem (CID 6918458), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.