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Chemical structure of FTI 277 HCl

GC16310

FTI 277 HCl

Also known as methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoate;hydrochloride

FTI 277 HCl is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling

ChemicalCAS180977-34-8MW484.07FormulaC22H30ClN3O3S2
CAS number
180977-34-8
Molecular weight
484.07
Formula
C22H30ClN3O3S2
Solubility
≥ 100mg/mL in DMSO
InChIKey
PIAFFJUUNXEDEW-PXPMWPIZSA-N
Catalogue number
GC16310
Brand
GLPBIO
Computed properties PubChem CID 88309922 · TPSA 120 Ų · H-bond donors 5 · H-bond acceptors 7
TPSA
120 Ų
H-bond donors
5
H-bond acceptors
7
Rotatable bonds
12
Heavy atoms
31

SMILES COC(=O)[C@H](CCSC)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC=C2.Cl

Computed descriptors from PubChem (CID 88309922), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.