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Chemical structure of FTI-277

GC36086

FTI-277

Also known as methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoate

FTI-277 is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling

ChemicalCAS170006-73-2MW447.61FormulaC22H29N3O3S2
CAS number
170006-73-2
Molecular weight
447.61
Formula
C22H29N3O3S2
Solubility
Soluble in DMSO
InChIKey
GKFPROVOIQKYTO-UZLBHIALSA-N
Catalogue number
GC36086
Brand
GLPBIO
Computed properties PubChem CID 3005532 · XLogP 3.2 · TPSA 120 Ų · H-bond donors 4
XLogP
3.2
TPSA
120 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
12
Heavy atoms
30

SMILES COC(=O)[C@H](CCSC)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC=C2

Computed descriptors from PubChem (CID 3005532), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.