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Chemical structure of AZ12601011

GC60610

AZ12601011

AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC50 of 18 nM and a Kd of 2·9 nM· AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4, TGFBR1, and ALK7· AZ12601011 inhibits mammary tumor growth

ChemicalMW313.36FormulaC19H15N5
CAS number
Molecular weight
313.36
Formula
C19H15N5
Solubility
DMSO: 5 mg/mL (15·96 mM)
Catalogue number
GC60610
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.