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Chemical structure of MRT00033659

GC60255

MRT00033659

Also known as N-[3-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]acetamide

MRT00033659 is a potent broad-spectrum kinase inhibitor of CK1 (IC50=0·9 ?M for CK1δ) and CHK1 (IC50=0·23 ?M)· MRT00033659, a pyrazolo-pyridine analogue, induces p53 pathway activation and E2F-1 destabilisation

ChemicalCAS1401731-54-1MW266.3FormulaC15H14N4O
CAS number
1401731-54-1
Molecular weight
266.3
Formula
C15H14N4O
Solubility
DMSO： 83·33 mg/mL (312·92 mM)
InChIKey
YFBPGSDPFRCNOY-UHFFFAOYSA-N
Catalogue number
GC60255
Brand
GLPBIO
Computed properties PubChem CID 66555775 · XLogP 2 · TPSA 70.7 Ų · H-bond donors 2
XLogP
2
TPSA
70.7 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
2
Heavy atoms
20

SMILES CC1=C2C=C(C=NC2=NN1)C3=CC(=CC=C3)NC(=O)C

Computed descriptors from PubChem (CID 66555775), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.