Loading...
Chemical structure of MRT 10

GC12192

MRT 10

Also known as N-[(3-benzamidophenyl)carbamothioyl]-3,4,5-trimethoxybenzamide

MRT 10 is a seven-transmembrane receptor smoothened (Smo) antagonist with an IC50 of 0·65 μM in the micromolar range in various Hedgehog (Hh) assays· MRT 10 binds to the Smo receptor at the level of the Bodipycyclopamine binding site· MRT 10 can be used for the research of cancer

ChemicalCAS330829-30-6MW465.52FormulaC24H23N3O5S
CAS number
330829-30-6
Molecular weight
465.52
Formula
C24H23N3O5S
Solubility
DMF： 33 mg/ml,DMSO： 33 mg/ml,DMSO：PBS (pH 7·2) (1：1)： 0·3 mg/ml
InChIKey
KVQVEZQDNHMQJV-UHFFFAOYSA-N
Catalogue number
GC12192
Brand
GLPBIO
Computed properties PubChem CID 1139102 · XLogP 4.3 · TPSA 130 Ų · H-bond donors 3
XLogP
4.3
TPSA
130 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
33

SMILES COC1=CC(=CC(=C1OC)OC)C(=O)NC(=S)NC2=CC=CC(=C2)NC(=O)C3=CC=CC=C3

Computed descriptors from PubChem (CID 1139102), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.