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Chemical structure of EZ-482

GC60158

EZ-482

Also known as N-[5-[(3-chlorophenyl)sulfamoyl]-2-hydroxyphenyl]-2-(3-methyl-4-oxophthalazin-1-yl)acetamide

EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 μM for apoE3 and apoE4

ChemicalCAS1016456-76-0MW498.94FormulaC23H19ClN4O5S
CAS number
1016456-76-0
Molecular weight
498.94
Formula
C23H19ClN4O5S
InChIKey
CLWDCBBEVQRZLY-UHFFFAOYSA-N
Catalogue number
GC60158
Brand
GLPBIO
Computed properties PubChem CID 24673104 · XLogP 3 · TPSA 137 Ų · H-bond donors 3
XLogP
3
TPSA
137 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
34

SMILES CN1C(=O)C2=CC=CC=C2C(=N1)CC(=O)NC3=C(C=CC(=C3)S(=O)(=O)NC4=CC(=CC=C4)Cl)O

Computed descriptors from PubChem (CID 24673104), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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