GC49620
GSK 417651A
Also known as 3,4-dihydro-1H-isoquinolin-2-yl-[2-(4-methoxyanilino)-1,3-thiazol-4-yl]methanone
GSK 417651A is a potent selectivity blocker of the canonical transient receptor channels (TRPC3/6), has block potency for hTRPC3 and hTRPC6 with IC50 values of 1260 nM and 500 nM, respectively
ChemicalCAS736945-96-3MW365.5FormulaC20H19N3O2S
- CAS number
- 736945-96-3
- Molecular weight
- 365.5
- Formula
- C20H19N3O2S
- Solubility
- DMSO： soluble
- InChIKey
- NTXBDULODNTCKP-UHFFFAOYSA-N
- Catalogue number
- GC49620
- Brand
- GLPBIO
Computed properties PubChem CID 1096735 · XLogP 4.1 · TPSA 82.7 Ų · H-bond donors 1
- XLogP
- 4.1
- TPSA
- 82.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 26
SMILES COC1=CC=C(C=C1)NC2=NC(=CS2)C(=O)N3CCC4=CC=CC=C4C3
Computed descriptors from PubChem (CID 1096735), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il