GC44214
ML-162
Also known as 2-(3-chloro-N-(2-chloroacetyl)-4-methoxyanilino)-N-(2-phenylethyl)-2-thiophen-2-ylacetamide
ML-162 is a GPX4 inhibitor that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively)
ChemicalCAS1035072-16-2MW477.4FormulaC23H22Cl2N2O3S
- CAS number
- 1035072-16-2
- Molecular weight
- 477.4
- Formula
- C23H22Cl2N2O3S
- Solubility
- 1mg/mL in ethanol, 25mg/ml in DMSO, 10mg/mL in DMF
- InChIKey
- UNVKYJSNMVDZJE-UHFFFAOYSA-N
- Catalogue number
- GC44214
- Brand
- GLPBIO
Computed properties PubChem CID 3689413 · XLogP 5.2 · TPSA 86.9 Ų · H-bond donors 1
- XLogP
- 5.2
- TPSA
- 86.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Rotatable bonds
- 9
- Heavy atoms
- 31
SMILES COC1=C(C=C(C=C1)N(C(C2=CC=CS2)C(=O)NCCC3=CC=CC=C3)C(=O)CCl)Cl
Computed descriptors from PubChem (CID 3689413), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il