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Chemical structure of ML-179

GC44215

ML-179

Also known as 3-cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione

ML-179 is a potent inverse agonist of liver receptor homolog-1 (LRH-1) (IC50 = 320 nM) with maximum efficacy of 40% repression

ChemicalCAS1883548-87-5MW422.4FormulaC21H25F3N4O2
CAS number
1883548-87-5
Molecular weight
422.4
Formula
C21H25F3N4O2
Solubility
DMSO： 10 mg/ml
InChIKey
MFABFKUNLDYKGH-UHFFFAOYSA-N
Catalogue number
GC44215
Brand
GLPBIO
Computed properties PubChem CID 45100448 · XLogP 3.8 · TPSA 55.9 Ų · H-bond donors 1
XLogP
3.8
TPSA
55.9 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
30

SMILES C1CCC(CC1)N2C(=O)C=C(NC2=O)N3CCN(CC3)C4=CC=CC(=C4)C(F)(F)F

Computed descriptors from PubChem (CID 45100448), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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