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Chemical structure of ML-109

GC31490

ML-109

Also known as N-[4-[[5-(3-benzyl-5-hydroxy-4-oxo-1,2-dihydroquinazolin-2-yl)-2-methoxyphenyl]methoxy]phenyl]acetamide

ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM

ChemicalCAS1186649-91-1MW523.58FormulaC31H29N3O5
CAS number
1186649-91-1
Molecular weight
523.58
Formula
C31H29N3O5
Solubility
DMSO： 83·33 mg/mL (159·15 mM)
InChIKey
JRVXFGNCHKHBPA-UHFFFAOYSA-N
Catalogue number
GC31490
Brand
GLPBIO
Computed properties PubChem CID 25246343 · XLogP 5.1 · TPSA 100 Ų · H-bond donors 3
XLogP
5.1
TPSA
100 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
39

SMILES CC(=O)NC1=CC=C(C=C1)OCC2=C(C=CC(=C2)C3NC4=C(C(=CC=C4)O)C(=O)N3CC5=CC=CC=C5)OC

Computed descriptors from PubChem (CID 25246343), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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