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Chemical structure of GSK-J5 (hydrochloride)

GC43794

GSK-J5 (hydrochloride)

Also known as ethyl 3-[[2-pyridin-3-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate;hydrochloride

The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer

ChemicalCAS1797983-32-4MW454FormulaC24H27N5O2•HCl
CAS number
1797983-32-4
Molecular weight
454
Formula
C24H27N5O2•HCl
Solubility
DMF： 30 mg/ml,DMF：PBS (pH 7·2); (1：7)： 0·1 mg/ml,DMSO： 30 mg/ml,Ethanol： 20 mg/ml
InChIKey
QQHQMHJAOKADED-UHFFFAOYSA-N
Catalogue number
GC43794
Brand
GLPBIO
Computed properties PubChem CID 126456082 · TPSA 80.2 Ų · H-bond donors 2 · H-bond acceptors 7
TPSA
80.2 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
32

SMILES CCOC(=O)CCNC1=CC(=NC(=N1)C2=CN=CC=C2)N3CCC4=CC=CC=C4CC3.Cl

Computed descriptors from PubChem (CID 126456082), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.