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Chemical structure of CX-5011 (sodium salt)

GC43334

CX-5011 (sodium salt)

Also known as sodium 5-(3-ethynylanilino)pyrimido[4,5-c]quinoline-8-carboxylate

CX-5011 is a highly selective and potent inhibitor of protein kinase CK2 (IC50 = 0·175 nM for native CK2), a pro-survival and anti-apoptotic kinase highly expressed in cancer cells

ChemicalCAS1333382-30-1MW362.3FormulaC20H11N4O2•Na
CAS number
1333382-30-1
Molecular weight
362.3
Formula
C20H11N4O2•Na
Solubility
Soluble in DMSO
InChIKey
FSIFELDKZUCPMJ-UHFFFAOYSA-M
Catalogue number
GC43334
Brand
GLPBIO
Computed properties PubChem CID 70702100 · TPSA 90.8 Ų · H-bond donors 1 · H-bond acceptors 6
TPSA
90.8 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
27

SMILES C#CC1=CC(=CC=C1)NC2=NC3=C(C=CC(=C3)C(=O)[O-])C4=CN=CN=C42.[Na+]

Computed descriptors from PubChem (CID 70702100), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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