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Chemical structure of CX-4945 sodium salt

GC11325

CX-4945 sodium salt

Also known as sodium 5-(3-chloroanilino)benzo[c][2,6]naphthyridine-8-carboxylate

CX-4945 sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'

ChemicalCAS1309357-15-0MW371.75FormulaC19H11ClN3NaO2
CAS number
1309357-15-0
Molecular weight
371.75
Formula
C19H11ClN3NaO2
Solubility
Soluble in DMSO
InChIKey
ODDAAPQSODILSN-UHFFFAOYSA-M
Catalogue number
GC11325
Brand
GLPBIO
Computed properties PubChem CID 49788959 · TPSA 77.9 Ų · H-bond donors 1 · H-bond acceptors 5
TPSA
77.9 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
26

SMILES C1=CC(=CC(=C1)Cl)NC2=NC3=C(C=CC(=C3)C(=O)[O-])C4=C2C=CN=C4.[Na+]

Computed descriptors from PubChem (CID 49788959), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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